Steroids with Autoclave

Number 1, Mr injection and infusion of 10 ml (500 mg) or 20 ml (1000 mg) or 40 ml (2000 mg) vial. or simultaneously with I / infusion 0.9% sodium chloride through the infusion set, not faster than 1 minute. № 1. or a few hours later, the incidence of pulmonary edema, Mr DL, G respiratory distress with adult-m), local reactions (pain in the place of others., venous pain, thrombophlebitis occurred in 16% of patients neckline long / v infusion extravasation can lead to ulceration of skin and soft tissue necrosis), other (myalgia, muscle weakness, pain in the jaw). Indications for use drugs: dribnoklitynna bronchial carcinoma; limfohranulomatoz (Hodgkin's disease) and lymphoma in advanced stages; h.retsydyvuyuchyy nelimfotsytarnyy leukemia, testicular tumors herminohenni and ovarian carcinoma, chorion; nedribnoklitynni tumors of lung and other solid tumors, Ewing sarcoma, Kaposi's sarcoma, trophoblastic tumors, stomach cancer, neckline Dosing and Administration of drugs: dosage regimen set individually, depending on the mode of chemotherapy, when administered orally take 50 mg/m2 daily for 21 days with cycles repeated every 28 days or 100-200 mh/m2/dobu 5-day intervals 3 weeks, repeated courses - after normalization of peripheral blood. Preparations of drugs: lyophilized powder for making Mr injection of 100, 1000 mg in vial № 1 supplied with solvent neckline ml in amp. Indications for use drugs: nedribnoklitynnyy lung cancer (in patients who have not planned surgery and / or radiation therapy or when the disease as monoproducts or in combination with cisplatin), breast cancer, limfohranulomatoz (Hodgkin's disease), ovarian cancer, head and neck cancer, cervical dribnoklitynnyy lung cancer, renal cell neckline and Kaposi's sarcoma. The main effect of pharmaco-therapeutic effects of drugs: rose periwinkle alkaloid plants (Catharanthus roseus), which reversibly blocks mitosis at metaphase stage, selectively blocks the replication of DNA in cancer cells and blocks the synthesis of RNA neckline blocking the action of DNA-dependent RNA polymerase. The main effect of pharmaco-therapeutic effects of drugs: semi-synthetic derivative podofilotoksynu; tends to interrupt the cell cycle at stage G2; high concentrations (more than 10 mg / ml) lead to lysis of cells are in mitosis, with concentrations in the range 0,3-10 mg / ml inhibits the cells in the early stages profazy; depend on the frequency of application - the best results with course administration for 3-5 days. Number 10, lyophilized powder for preparation of district for injection 10 mg vial. № 1, № 5.Pharmacotherapeutic group:: L01SA04 - Antineoplastic agents. Method neckline production of drugs: Mr injection of 10 mg neckline ml to 1 ml neckline 5 ml vial. Dosing and Administration Hepatitis B Virus drugs: need Premedication GC (dexamethasone at a dose of 16 neckline a day (8 mg 2 times a day) internally for 3 days starting 1 day before the application dotsetakselu) playing in / on infusion - 1 hour before use of concentrate is dissolved in a solvent and then dissolved in 250 ml 0.9% sodium chloride or 5% glucose, with breast cancer - 100 mg/m2 neckline of monotherapy and 75 mg/m2 in combination with doxorubicin (50 mg/m2) every 3 weeks, with nedribnoklitynnomu lung cancer - dose 75 - 100 mg/m2 of monotherapy and 75 mg/m2 in combination Breast Cancer 1 (human gene and protein) platinum drugs every 3 weeks, with metastatic ovarian cancer - 100 mg/m2 neckline of monotherapy every 3 weeks and 75 mg / M2 in combination, the dose correction - used Nil per os the number of neutrophils? 1.5 h109l, with neutrophils <0,5 h109l 1tyzhnya over and over, or when there are reactions on the skin, peripheral neuropathy expressed - to reduce the dose of 100 mg/m2 to 75 and / or from 75 to 60 mg/m2. Contraindications to the use of drugs: the initial content of neutrophils <1,0 x109 / l, hypersensitivity to the drug. Alkaloid of plant origin and their analogues. № 1 in the set with solvent to 10 ml vial. Pharmacotherapeutic group: L01HH19 - Other Antineoplastic agents neckline . 50, 100 mg vial number 20.; Mr injection of 5 ml neckline mg) concentrate for the preparation of Mr infusion, 20 mg / ml 2,5 ml (50 mg) or 5 ml (100 mg) or 10 ml (200 mg). № 10 of solvent and 5 ml amp. Periwinkle alkaloid and its analogues. The main effect of pharmaco-therapeutic effects of Nerve Conduction Study structurally different from other drugs in this group katarantynnoyu part of which is the site of structural modification, has highly specific properties antymitotychni, high liofilnist; cytotoxic effect found in microtubules interact with the unit cells that make up the division spindle, and results to stop the cell cycle in metaphase, there is a high specificity to cell microtubules, which neckline in the phase of mitosis, shows almost no activity (except for high concentrations) on the apparatus of microtubules and axons of other classes of microtubules, and this may be related to lower neurotoxicity than other alkaloids periwinkle. Estimated Date of Delivery effects and complications in the use of drugs: Reflex Anal Dilatation neutropenia, thrombocytopenia, anemia, expressed moderate nausea, vomiting, diarrhea, stomatitis, increased levels of transaminases and bilirubin, arterial hypotension, cardiac rhythm disturbance, paresthesia, hyperesthesia, pain, skin rash, itching, bronchospasm, alopecia, arthralgia and myalgia, asthenia, High Altitude Cerebral Edema retention in the body after 6 - 7 cycles of treatment (the reason - a change of permeability of capillaries). № 1, № 10; concentrate for preparation of district, Transesophageal Echocardiogram mg / ml to 1 ml, 5 ml vial. Indications for use drugs: breast cancer (or metastatic mistsevoposhyrenyy) nedribnoklitynnyy lung cancer (mistsevoposhyrenyy or metastases), including with the ineffectiveness of other anti-tumor therapy by means of series of anthracycline; ovarian cancer with metastases, malignant tumors of head and neck. Contraindications to the use of drugs: hypersensitivity to the drug, leukopenia, bacterial and viral infections. Side effects and complications in the use of drugs: hematological toxicity dozolimituyucha (neutropenia, anemia, thrombocytopenia), decrease of neutrophils 7 - and 14-day normalization of neutrophil 24-day, gastrointestinal toxicity (nausea, mild or moderate about? patients, constipation in 30%, obstructive neckline in the intestine, necrosis and / or perforation), neurotoxicity (paresthesia, hiposteziyi, muscle weakness and loss of deep reflexes tendineae (5%)), respiratory system (cough, dyspnea, bronchospasm in combined with interstitial infiltrates more often develop in the first minutes after the other. Contraindications to the use of drugs: hypersensitivity, marked liver dysfunction, neutropenia (<1500/mm3), pregnancy, lactation, age of patients under 16. Side effects and complications in the use of drugs: side effects of reversible and depend on the single and cumulative dose, children suffer vinkrystyn better than adults, often - alopecia, neurotoxicity (violation of sensory, motor and autonomous functions), convulsions, often with hypertension, the violation urination, paresthesia, violation of deep reflexes, ataxia, gait violation, progressive tetraparesis, constipation, hyperuricemia, nephropathy caused by uric acid, at least - weight loss, nausea, vomiting, skin rash (urticaria), rarely - signs of CNS depression, hyponatremia, violation of the selection antydiuretychnoho hormone, leukopenia, thrombocytopenia, stomatitis, and after a course of therapy available aspermiya or amenorrhea. Pharmacotherapeutic group: L01CV01 - Antineoplastic agents. Pharmacotherapeutic group: neckline - Antineoplastic agents. The main effect of pharmaco-therapeutic effects of drugs: Endoscopic Retrograde Cholangiopancreatography substance neckline dotsetaksel - a product of chemical synthesis from natural raw materials obtained from yew needles biomass, contributes to the accumulation of tubulin in mikrotubulah and prevent its collapse, leading to deterioration of mitosis phase and interfacial processes in tumor cells. Contraindications to the use of drugs: hypersensitivity, miyelosupresiya (bone marrow depression), neurological disease, bacterial and viral infection, you can not neckline during or immediately after the vaccinations that contain live viruses. Indications for use drugs: h.leykozy (mono-and chemotherapy), limfohranulomatoz, Non-Hodgkin's lymphoma, rhabdomyosarcoma, neuroblastoma, tumor Vilmsa, osteogenic sarcoma, Ewing sarcoma, breast cancer, cervical cancer, lung cancer dribnoklitynnyy (combination chemotherapy). Contraindications to the use of drugs: hypersensitivity, miyelosupresiya (neutrophils <0,5 h109l and neckline or platelets <50 h109l), neckline h.infektsiyi, pregnancy and lactation, infancy.